A groundbreaking new analysis has uncovered evidence that Pfizer’s Covid mRNA shots may have contained bacterial DNA fragments with dangerous immune-activating signatures.
The discovery is raising urgent questions about how regulators ever allowed the injections to reach the public.
The findings were revealed in a preprint published by molecular biologist Kevin McKernan.
McKernan used advanced Oxford Nanopore sequencing technology to analyze a Pfizer vaccine lot (FL8095).
His results revealed:
Bacterial-style DNA methylation marks (m6A), a fingerprint of contamination from E. coli–derived DNA.
Evidence of incomplete linearization, meaning the DNA used to manufacture the shots may not have been fully processed, leaving behind problematic fragments.
Signals that the contamination could, in theory, trigger powerful immune responses, potentially leading to harmful side effects.
These findings raise serious questions about the integrity of the health regulatory process during the declared COVID-19 pandemic.
DNA “Fingerprints” Expose Contamination
According to McKernan’s sequencing run of nearly 600,000 reads, the “vaccine” lot displayed widespread methylation at GATC motifs, a classic hallmark of bacterial Dam methyltransferase activity.
In simple terms, the DNA fragments in Pfizer’s product looked like they came from common E. coli production strains, not “clean” DNA sources free of bacterial signatures.
Shockingly, McKernan also detected read-through sequences crossing the cut site that should have fully linearized the plasmid DNA template.
This suggests sloppy or incomplete manufacturing processes left behind uncut plasmid fragments, a red flag for quality control.
Why This Matters
Bacterial-style DNA methylation is not just a cosmetic defect.
Scientific literature shows that such fragments can trigger cGAS–STING immune pathways, setting off inflammatory cascades and cytokine storms.
McKernan stresses his preprint is exploratory and does not prove clinical consequences but the mechanistic risk is real and demands urgent investigation.
Regulatory and Safety Crisis
The revelations add to a growing body of evidence suggesting regulators overlooked or concealed critical data about mRNA vaccine safety.
Earlier this week, Japanese documents revealed the biodistribution of Pfizer’s vaccine into organs like the liver, spleen, and adrenal glands.
However, this information was conveniently missing from U.S. FDA filings.
McKernan’s latest work now shows contamination with bacterial-style DNA fragments that could further compromise safety.
Independent scientists are calling for:
• Lot-by-lot transparency on DNA contamination levels.
• Mandatory use of bacterial strains that minimize dangerous methylation marks.
• Functional testing of vaccine DNA fragments in cell and animal models.
Without such steps, McKernan warns, the public cannot be assured these products are free from harmful contaminants.
The Bigger Picture
This report comes amid mounting concerns that Covid mRNA injections have been linked to immune dysregulation, cardiac injuries, and even cancer signals.
However, regulators continue to insist the products are “safe and effective.”
As Slay News has previously reported, other independent analyses show residual DNA fragments, SV40 enhancer sequences, and spike protein persistence in the body long after “vaccination,” findings that health authorities have downplayed or ignored.
Now, with McKernan’s forensic sequencing data, the case for a full investigation into Pfizer’s manufacturing and regulatory oversight has never been stronger.
READ MORE – Major Study Confirms Every Covid ‘Vaccine’ Dose ‘Shortens the Lives of Recipients’
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